In many cases, he focused his attention to the lives of women and identified how a woman devoted to Jesus should live her life.
During one of these illnesses (about the winter of 373–374), he had a vision that led him to lay aside his secular studies and devote himself to God.
He seems to have abstained for a considerable time from the study of the classics and to have plunged deeply into that of the Bible, under the impulse of Apollinaris of Laodicea, then teaching in Antioch and not yet suspected of heresy.
Soon after the death of his patron Damasus (10 December 384), Jerome was forced by them to leave his position at Rome after an inquiry was brought up by the Roman clergy into allegations that he had an improper relationship with the widow Paula.
Still, his writings were highly regarded by women who were attempting to maintain a vow of becoming a consecrated virgin.
In August 385, he left Rome for good and returned to Antioch, accompanied by his brother Paulinian and several friends, and followed a little later by Paula and Eustochium, who had resolved to end their days in the Holy Land.
In the winter of 385, Jerome acted as their spiritual adviser.In Rome he was surrounded by a circle of well-born and well-educated women, including some from the noblest patrician families, such as the widows Lea, Marcella and Paula, with their daughters Blaesilla and Eustochium.The resulting inclination of these women towards the monastic life, away from the indulgent lasciviousness in Rome, and his unsparing criticism of the secular clergy of Rome, brought a growing hostility against him among the Roman clergy and their supporters.Jerome initially used classical authors to describe Christian concepts such as hell that indicated both his classical education and his deep shame of their associated practices, such as pederasty which was found in Rome.Although initially skeptical of Christianity, he was eventually converted. Duns Scotus William of Ockham Alexander of Hales Henry of Ghent Francis Mayron Luis de Molina Peter Lombard Peter Abelard Giles of Rome; c.